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Thursday, September 27, 2007

Canada has a budget surplus of CA$13.8 billion for the 2006–2007 fiscal year, totaling 1% of Canada’s gross domestic product (GDP), Finance Minister Jim Flaherty announced today. The record surplus was boosted by revenue from government corporations to $14.2 billion, far exceeding the government’s projections of $9.2 billion and surpassing the record set by the previous year’s $13.2 billion surplus.

By federal law, all surplus must be used to pay down Canada’s debt, and is not available for spending. $90 billion in debt payments over the last ten years have reduced its debt to $467 billion or 32.3% of national GDP, its lowest level in a quarter century. The announced debt payment is the largest in Canadian history.

The payment also reduced Canada’s annual interest payments by $725 million, which the government pledged to pass on to taxpayers through tax returns and reduced income taxes. The Conservative’s “Tax Back Guarantee”, proposed in the March budget, promises that money saved on interest payments will be deducted from Canadians’ taxes. The Globe and Mail predicts the tax returns will be 30–40 dollars per taxpayer.

Canada has posted ten consecutive budget surpluses in the last decade. The Canadian economy, the 8^th largest in the world, has benefited from rising global demand for its export commodities, particularly oil and copper, as well as record corporate profits. This surplus was further increased by a $700 million drop from expected government spending.

Prime Minister Stephen Harper cautioned that the Canadian economy is still facing “tough times” in its forestry, manufacturing, and some export industries. Critics point out that the Conservative government had said Canadians were overtaxed when they took office, and had vowed to eliminate “surplus surprises”.

Sunday, December 26, 2004

Indian Ocean – The death toll continues to grow and millions face a homeless life in the new year as coastal communities in south Asia struggle against continued aftershocks and flooding caused by the largest earthquake to strike the planet in more than a generation.

The magnitude 9.0 undersea megathrust earthquake struck off the western coast of Sumatra, Indonesia on December 26, 2004, at 00:58:50 UTC (or 07:58:50 local time in Jakarta and Bangkok).

The earthquake was the strongest in the world since the 9.2-magnitude Good Friday Earthquake which struck Alaska, USA in 1964, and the fourth largest since 1900. More than 140,000 deaths[1] were caused by resulting tsunami, which in Thailand were up to 10 meters (33 feet) tall, and struck within three hours of the initial event.

Multiple tsunamis struck and ravaged coastal regions all over the Indian Ocean, devastating regions including the Indonesian province of Aceh, the coast of Sri Lanka, coastal areas of the Indian state of Tamil Nadu, the resort island of Phuket, Thailand, and even as far away as Somalia, 4,100 km (2,500 mi) west of the epicenter.

While the earthquake and the tsunamis are no longer ongoing (other than aftershocks), the humanitarian and economic crisis generated by the disaster is still ongoing. This report will attempt to cover the crisis as it continues to develop.

Tuesday, March 15, 2005

Beijing’s utilities are cracking down on manhole cover thefts by removing the incentive to steal them. A pilot program is using a new material with negligible recycling value in over 2,921 installations of various types.

“We are still looking for the perfect substitutes for the manhole covers,” said city spokesman Wang Xin.

Over 240,000 covers were stolen from Beijing’s streets in 2004, nearly half of the 600,000 installations scattered throughout the city.

The high recycling value of the metal used to manufacture the previous models led to a crime wave of thefts, driven by illegal scrap metal dealers who purchased them for approximately US$2.4 dollars.

The covers cost between US$145 and US$182 to replace.

18 December 2004

Emergency hospital during 1918 influenza epidemic, Camp Funston, Kansas (source: National Museum of Health and Medicine, AFIP).

A bout of the flu can be mild. In young, healthy adults, many infections pass unnoticed. But sometimes the influenza virus evolves into a strain that decimates its victims. The worst known strain swept the world in the Fall of 1918, infecting 500-1000 million and killing 40-100 million, about 2-5% of people.

There are several theories about where the pandemic began, but the likeliest origin was in Haskell County, Kansas, in the United States. People in the sparsely populated county, where farmers raised pigs, poultry, cattle, and grain, began suffering from influenza in late January 1918. Unusually for flu, it was young, healthy adults who were hardest hit. Victims fell ill suddenly, many progressing to pneumonia and dying, often within days. Within weeks, however, the epidemic ended. The natural geographic isolation of this community normally might have contained the fatal flu in a sort of unintentional quarantine, but the First World War intervened. Men were uprooted from their home towns and congregated in huge numbers in army camps for training and then shipping out to other camps or to fight in Europe. The destination for men from Haskell County was Camp Funston, part of Fort Riley, Kansas, where the first influenza case was reported in early March. As soldiers moved among camps, the virus spread. Within two months, the epidemic spread to most of the army camps and most of the largest cities in the United States. As American soldiers went to France, so did the virus, spreading first from the port of Brest.

The flu then spread worldwide. The pandemic reached its height in the Fall of 1918. Spain was affected early, and because Spain was not fighting in the World War, there was no wartime censorship, and news of the outbreak became widely known, leading to the flu being called the Spanish Flu in many countries. In Spain, however, it was called French Flu or the Naples Soldier. In India, about 12 million people died of flu. In some US cities, people died so quickly that morticians couldn’t cope with the bodies. According to Jessie Lee Brown Foveaux, who worked in the Fort Riley laundry during the epidemic: “They were piling them up in a warehouse until they could get coffins for them.”

The disease started with cough, then headache. Temperature, breathing and heart rate increased rapidly. In the worst cases, pneumonia came next, the lungs filling with liquid, drowning the patients and turning them blue from lack of air. Patients bled from every orifice: mouths, noses, ears, eyes. Those who survived often suffered temporary or permanent brain damage. Several million developed encephalitis lethargica, in which victims were trapped in a permanent sleeplike and rigid state, as portrayed in the 1990 movie “Awakenings.” In others, normal thought processes were impaired. During negotiations to end World War I, US President Woodrow Wilson was struck with flu, and people around him noted that his mental abilities never fully recovered. The French leader George Clemenceau had wanted harsher punishment of Germany than Wilson had desired. Clemenceau may have convinced Wilson in his weakened state to accept such harsh terms, which may have been one of the factors causing World War II.

Since flu is highly contagious early in the illness, even before symptoms appear, strict quarantine may be necessary to stop its spread during an epidemic. Australia kept its 1918 flu death rate relatively low by enforcing quarantines. However, in many parts of the world, public health officials hesitated to impose such measures, giving the disease time to gain a foothold. In the US city of Philadelphia, a rally of half a million people was planned in September 1918 to sell bonds to fund the war, at just the time when the flu started to infect residents. Although doctors warned the public health director to cancel the rally, he wanted to meet the city’s quota to raise money for the war and refused to cancel the event. Within days after the rally, half a million city residents caught the flu.

Why was the 1918 flu so deadly? The influenza virus wasn’t preserved at the time of the outbreak, at least on purpose. But in the late 1990s researchers Ann Reid, Jeffery K. Taubenberger, and their colleagues extracted and sequenced the genetic material of the virus, RNA, from tissue of victims who died in the pandemic. They used bits of lung that were preserved in formalin from victims on army bases or from victims buried in permafrost in the Alaskan village of Brevig Mission, where flu killed 85% of adults. Comparisons with known flu viruses in humans, pigs, and birds suggest that some genes of the 1918 virus came from birds or an unknown animal source. Other scientists then were able to show that the amino acid sequence of hemagglutinin protein from the 1918 virus had several changes from other flu viruses that may have helped it to easily bind and invade human cells, and that made the virus look different enough from earlier flu virus strains that people had no immunity.

The possibility exists that another flu pandemic will sweep the world like the one in 1918. In 2004, an H5N1 influenza virus has killed millions of birds and at least 30 people in southeast Asia. So far this virus strain has not evolved the ability to pass directly from human to human, but that possibility becomes more likely as the bird flu pandemic continues and humans remain in contact with chickens, ducks, and other birds. The virus has killed two-thirds of people reported to be infected. Dr. Tim Uyeki, an epidemiologist for the US Centers for Disease Control, says, “you have the ingredients in Asia right now for a public health disaster.”

But since sequences of this bird flu virus are known, it may be possible to develop a vaccine or set of vaccines to protect against it. At a special meeting of influenza experts on November 11th and 12th, World Health Organization influenza program chief Klaus Stohr said, “It is not only possible, but also important, that influenza pandemic vaccines be made available… and there’s a shared responsibility needed to make that happen…. We have a huge window of opportunity now.”

Monday, August 7, 2006

Dogs can be trained to detect early and late stages of lung and breast cancer accurately according to a study published by California scientists in the little-known scientific journal Integrative Cancer Therapies.

The study took place over the last five years at the Pine Street Foundation, a non-profit organization which conducts evidence-based research on integrative medicine (combining complementary and alternative medicine and mainstream medicine). Michael McCulloch and colleagues used three Labrador Retrievers and two Portuguese Water Dogs, both common pets, that received basic behavioral dog training. The researchers trained the dogs to lie down next to a sample from a cancer patient and to ignore other samples.

The samples used were breath samples from 55 patients with lung cancer and 31 with breast cancer — the two types of cancer with the highest mortality rates in the United States.

After the training phase, the dogs’ accuracy diagnosis was tested in a double-blind experiment. Among lung cancer patients, the sensitivity and specificity were 99% accurate and for breast cancer sensitivity was 88% and specificity 98%. Because these figures seem almost too good to be true, cancer experts are the same time baffled and skeptical. The authors of the study themselves also say replication of the study is needed.

Importantly, this was independent of the cancer stage, meaning the dogs were able to pick up the scent of cancer in its early stages. This is important because in many cases, the success of any treatment depends on early diagnosis. However, the researchers don’t believe this will lead to the use of dogs in the clinic soon, rather they want to find out which chemicals are actually sensed by the canines, because they could be used in laboratory assays. “It’s not like someone would start chemotherapy based on a dog test,” Dr. Gansler of the American Cancer Society said, “They’d still get a biopsy.”.

The researchers were inspired by anecdotal reports about dogs detecting cancer. In 1989, a British women consulted with her family physician because her Dalmatian kept licking a mole on her leg. At biopsy it showed to be malignant melanoma. When diagnosed too late this form of cancer has a poor survival rate, but in this case early surgery was made possible, and the women survived. Prior studies showed that breath samples from patients with lung cancer or breast cancer contain distinct biochemical markers. This provides a basis for the hypothesis that some cancer types produce volatile chemicals that dogs could smell. A study published in the British Medical Journal already proved that dogs could use their exquisite sense of smell to detect bladder cancer in urine samples, but they were only correct in 41% of cases, and another study provided preliminary evidence that dogs could detect melanomas.

This doesn’t mean you can show your breasts to your dog and it will tell you if you have cancer, other physicians caution, and scientists do not advise people to train their dogs to sniff for cancer. Unresolved issues from the study include the fact that subjects were required to breathe deeper than normal, so it’s not sure whether dogs can smell cancer in normal breath. Also, whether this is a permanent skill that would be retained by dogs was not tested.

Finally, there are concerns that could arise over liability issues: who would be responsible when the dog makes a mistake?

Current detection methods for both lung and breast cancer are not flawless. For lung cancer, chest X-ray and sputum cytology (detecting cancer cells in coughed up fluid) fail to detect many early cases, and CT scan produces many false-positive results unless combined with expensive PET scans. Although it might be comparing apples and oranges, a $2.5 million CT scanner has an accuracy of 85 to 90%. Mammography also produces false-positive results, and it may be difficult in women with dense breast tissue. As such, another type of “pet”-scan, using dogs as a biological assay, might prove feasible for screening if supported by further research. Current tests are also expensive so the use of dogs for preliminary cancer testing could prove to be an affordable alternative for countries in the developing world.

Thursday, November 16, 2006

Two elderly women whose CCTV pictures were shown in newspapers across the UK on Thursday after they were caught on camera stealing a bag at a railway station in Sunderland have turned themselves in.

The police has announced that women admitted the offence and have received an official caution in a case variously dubbed the “Grey Train Robbery” and “Gran Larceny.”

The women contacted police services after the case received major newspaper and media coverage under headlines such as “Nans on the Run” and “Artful Codgers.”

A security camera image released by police showed two grey-haired women, in their 60s or 70s, wearing knee-length skirts, white blouses and overcoats at Sunderland station.

Police had appealed for help in finding the women after a student’s bag was stolen from a station platform.

“They handed themselves in,” police announced in a statement. “They subsequently were interviewed and admitted the offence. Both received police cautions.”